physiologically based population adme simulator simcyp version 11 (Simcyp)
90
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Simcyp
physiologically based population adme simulator simcyp version 11
Physiologically Based Population Adme Simulator Simcyp Version 11, supplied by Simcyp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/physiologically+based+population+adme+simulator+simcyp+version+11/simcyp+v19/pm23584886-45-10-13
Average 90 stars, based on 1 article reviews
Physiologically Based Population Adme Simulator Simcyp Version 11, supplied by Simcyp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/physiologically+based+population+adme+simulator+simcyp+version+11/simcyp+v19/pm23584886-45-10-13
Average 90 stars, based on 1 article reviews
physiologically based population adme simulator simcyp version 11 - by Bioz Stars,
2026-09
90/100 stars
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other:Article Title: Optimization of drug-drug interaction study design: comparison of minimal physiologically based pharmacokinetic models on prediction of CYP3A inhibition by ketoconazole. Article Snippet: Ketoconazole is a potent CYP3A inhibitor used to assess the contribution of CYP3A to drug clearance and quantify the increase in drug exposure due to a strong inhibitor.. Physiologically based pharmacokinetic (PBPK) models have been used to evaluate treatment regimens resulting in maximal CYP3A inhibition by ketoconazole but have reached different conclusions.. We compare two PBPK models of the ketoconazole-midazolam interaction, model 1 (Chien et al., 2006) and model 2 implemented in Simcyp (version 11), to predict 16 published treatment regimens. |